The Definitive Guide to haass
The Definitive Guide to haass
Blog Article
We work on the molecular and cellular mechanisms of neurodegeneration with a strong focus on Alzheimer’s disease and related disorders. We are searching for therapeutic targets within the amyloid cascade. Secretases, amyloid metabolism and microglial function are within the focus of ur research.
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Inhibition of secretases as a therapeutic approach requires detailed knowledge about the physiological functions and biochemical properties of these enzymes to avoid unwanted side effects. Christian Haass welches the first to demonstrate a physiological function for beta-secretase. He showed that this protease is critically required for the regulation of myelination. Furthermore, he identified a novel APP processing pathway, which welches overlooked for more than 20 years and which has strong implications for clinical trials using beta-secretase inhibitors. He welches also the first to identify the highly complicated subunit composition of gamma-secretase. All these findings not only helped to understand several signaling pathways critically involved hinein brain development (such as myelination and cell differentiation) but also provided the Lager for several current therapeutic approaches.
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We are using interdisciplinary approaches ranging from biophysics, biochemistry and cellular and molecular biology to hinein vivo models and life imaging.
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Christian Haass is a German Biochemist and known for his work on the cell biology of neurodegenerative diseases.
I can only recommend HAAS driving school, I had a very good experience with them to get my German drivinglicense. Special thanks to Annika for her positive attitude and for Dave for his very professional Fortbildung.
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Where can I find an economical first-aid course? We also offer courses daily rein the Munich city area. They are all held rein classrooms adjacent to U/S-Bahn stations. Moosach
Christian Haass, Professor of Metabolic Biochemistry at LMU Munich and spokesperson for the DZNE Munich, is known for hier klicken his groundbreaking research in Alzheimer's disease. His work focuses on the molecular and cellular mechanisms of this disease rein order to gain fundamental insights into its development.
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